International Journal of Dentistry Research 2024; 9(2): 42-45 ; DOI:10.31254/dentistry.2024.9203
Diagnosis and treatment of an unusual case with multiple intra-oral growths of neural tissue origin
Moumita Nayek1 , Debarati Bhowmick2 , Surajit Mistry1 , Indrasri Das1 , Argha Rudra3
1. Associate Professor, Department of Periodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India
2. Assistant Professor, Department of Periodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India
3. Professor, Department of Periodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India
*Author to whom correspondence should be addressed.
Received: 8th July, 2024 / Accepted: 27th August, 2024 / Published : 30th April, 2024
A 27-year-old female patient in this case study had several growths along the lateral border and ventral surface of tongue. The patient also had multiple skin swellening and café au lait pigmentation. Histopathological examination revealed hyperplastic stratified squamous epithelium and proliferating fibrous tissue with chronic inflammatory infiltrates in the tongue growths. Immunohistochemical analysis using Sox 10, Ki67 and S100 markers confirmed high cellular proliferation and neural differentiation in the lesions, respectively. The findings led to the diagnosis of neurofibromatosis type I (NF1). This case highlights the importance of considering NF1 in the differential diagnosis of oral neurofibromas, especially in patients with multiple skin manifestations, and emphasizes the need for regular follow-ups to monitor disease progression and manage potential complications.
Café au Lait pigmentation, Nodules, Schwannoma, Ventral surface of tongue, Von Recklinghausen's disease.
HOW TO CITE THIS ARTICLE
Nayek M, Bhowmick D, Mistry S, Das I, Rudra A. Diagnosis and treatment of an unusual case with multiple intra-oral growths of neural tissue origin. Int J Dent Res 2024; 9(2):42-45. doi: 10.31254/dentistry.2024.9203
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.
